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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c1ef0130ee4662ce266307882e7502073b365ceabe9c7e22e082c0d8717714a' 
  AND token = 'L1sHa+gL0ysatAimkVFGWw2IIXyVhfOYAA/rp9sRLJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}