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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec1a6883d374ef26617e872c4beeb07a3b417704eacbe0c5f1ed5c44c22c038' 
  AND token = 'OsY0zjxhOvAnTehY/E0bomASAXuKcB0skTmn+K+pEzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}