SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9801cc8bfb75c4ee535786b88d082e308e5515b0969a85f98218a18e7a3ca3b0' 
  AND token = 'UhldMbT0T1lnmtDkzUuDaZaDLJl1+qyyi2ehN3pjK1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}