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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '439ea20c12b10aafe2912fe4165d5a47e0eddd9915a2a6d0ec7f731b099dedac' 
  AND token = 'iKi9IYQoaisFMg+sAEyrNprfdnkEeqGotMq+ddUX63I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}