SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf0a9c4313886b7601df6e3d5944ba5cece0ab46f1a1bfe43dec8e72fe504de' 
  AND token = '5lFEdarMiQIz5uBx2JZK7548vwqPInX1655NRZUwIWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}