SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f054a72945a986ca53dc47acce261d009a43774ce8ce91815e1fd762723daccf' 
  AND token = 'wYZmN8wPgXxFii0rTTODE1rClm4phU18DXJXVY/ZqeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}