SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0713078cc4b37d7595e09e15149bdffa357e6a5e53487b351c06e2a68720b7d4' 
  AND token = 'P6mgw/6+WL5keIrTfJdpfzh91JiI1MBQ/RYQ6ZXbIQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}