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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75d26053f4fba59a1770daffa5f95573627a3f551600ab660c346e40992e0d50' 
  AND token = 'FZe3AtImqyWTVy8g0Nz9QMbmdN4a/pF3UejNB80V3CM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}