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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9828eb10d8a0dc4a4b648af159b618a9fcde15052d7d51e7abc71b63b888bbb1' 
  AND token = 'F08uGaKZuRmN5wQsJWGxRvIDaLiUdCbNfqPfAwLj7E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}