SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdb4e4a2fd341dce2814007f5f3d59804373ad69e7bb359a816c5abfebb15894' 
  AND token = 'y2dvpy25V38ySGzQMYVUS73BZYTWMvKtSwGe/AfPdDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}