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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f4608fa16fd5c2009c48d4b4dff2ecf6ebbb8d854072104fa3c60ca465788b9' 
  AND token = 'K1ifT7Tc3PJgKv7S1TO26npbzjYgiZr1tWj+pj4rOtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}