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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '867aaae4f80f5b4f34ddd05e7d2b40f0b1ab7238e8d6a4d18665033dee410701' 
  AND token = 'nFHlO9pJhEIIiWhV0sUTsbfZwQaoRdQCrRBf+T/sh8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}