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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c2a3e9fcdf13f5908942350350a7a8cccd0b202399bd6156e1e76ca9b8d8997' 
  AND token = '0BIsRP05k1YSkdYDcS/VDQZHn1OwfKXtDE2HdeCIhHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}