SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e3e145906186bb14ed311c9dbc42a19cd0060bcbeddfc29e96342c97cdfddb' 
  AND token = 'AVjeWS72nfS6R6+abt5MfMWl3y/mK9+ORxc2Mmv9XrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}