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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41dfb9e40abb785b8ad0de59bbad33f344b803b647c66fb6e141517d8ad8c3e9' 
  AND token = 'FYMU386F7Z3CMCRqlxaNF/X4oTkxVSHDS1/wiY95TjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}