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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd63d4586947765ed49ae244afd0bb569d1e5d2ceaeb36de034d0e8c334ee8d19' 
  AND token = 'LMWfBiNiSyDa4QFT/+mIgx3hQ2Koe7D22Cs+xyUNukw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}