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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a9f8542ce95f14539fabe5a0361f6b47d2923aaf07282b925840c051b9cd6f' 
  AND token = 'ST/ipd0jDGSpNAiQMojhXukTBVxdnM19mZe2XGwl4Rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}