SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e72514c63ac3b75ed0013ee1aecdb6e71fa24927f948d8894e76fbc06203bfd0' 
  AND token = '4reBCAVhNgc7aSrn30Sb6K80DS9OxWrN9zC3FANUG4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}