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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '054ef4354fd960158d1f30177cf1223fa2a623b9b9891e9f0e01cbf2a734cc77' 
  AND token = '60jpNQ+++243kSCXKrj5dg15tqLT02IGYnIdKCulmek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}