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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c401f37bc59c27694202467c3ac097a6df99c19216468a014c02a1e10b3045a8' 
  AND token = 'sclMOoOvGg4sS9jn//0CnElFl8xaavVZ1AkQA7duloI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}