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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c486dd3c908eae5599c1a46dbceb74e56ceffbfe260ac2f5cb0db61d70b69d0' 
  AND token = 'qMJM3Q0XRnK9+Vwx6+6wpPtpMiXfNvB+RHpmx6tVjhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}