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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ffefe60c86cda9af396d5e661d6e498f7503f719e00ac568fa4019bafdab40' 
  AND token = '0RvC8tNDjMA3jfJfzSvUSBAf+9cIfAQQwbwzGCvxqPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}