SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fac32ed1da9922f58f7daeab98ad15821fc4e80907bcb74351116929f483b95' 
  AND token = 'Jj0IXxUe0tQOwIeuyPmOHI1TyBkCpWpm9Bduzw44NiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}