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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8946ae0a5d775e189c5e7e226fa5d332fb404e85b89f9641b8625f0ce08a6bfe' 
  AND token = '40t+vX3nuavpcMrLI8gO2hP4gIgeAVDBNzjlNoOB4Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}