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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '018e469340d42de5463673e3a8c2ea5fc318eaec827cd2e08f05335fd7c2b90e' 
  AND token = 'KhcfnPuKzZIkQtSkOldIs+1Chjmp8Xh/t4TQ3M1KkcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}