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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5ca3fa84fd729cc2840ef86c7f240d34d913a3243ad1fb2586258e832985c6' 
  AND token = 'w1k/uOZyY2Febs8+A19uv13/rSHW6VkSTCvC/pROR68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}