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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16467897491c2278a07fee30486f7efa7d04079af637fd3411df156d6ab407e6' 
  AND token = '5g2BsRYBGJ6/GV9/ncf9pCe3QQORuChIggEkSKU9JeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}