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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d1ccd547d8e8e4220cffd21309a221a22a772d1b517a20d917ddeb7dc7d108e' 
  AND token = '3o73Ej0kRCYPqgM9khZmH63Lmk++mjlKR2bLOJ7ihI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}