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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72015eb661a2370eefcb2a71c7f7beee500e5a4c3e5e4f72ff60b5191be5eb71' 
  AND token = '15MjaXznnGLvTlKI1r0Ylh2sg1qTzJ/RMMdiBTNdSDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}