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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4867b269bb8ce0cc8c3fa7a4b053027efb520c58c598de6c1d8223b6d9efacab' 
  AND token = 'llhLU5q/o/YGgAxS4N0oZ8uKCHHwKC67I8IAjWH8hoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}