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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee505ba36313f9edb48fb1592eeae03d627c47e94c1a32721375ca7158f476c2' 
  AND token = 'P/P7xnUohqhAKW2MYHfd9EtyBdt3XW22phG8kZeDggs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}