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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cc18e53b528a50ba14fb1215c1e34f2e0a0fe1114e0daa100684b2c41e90c7a' 
  AND token = 'dmz02NC/OQxUNUQrh4IF4rWXj3d42Lvzynq14HjOGUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}