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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec8e0a78d21f60635d5f7aa1b0b95d708186abcbe3c184c5dfbd34753ceb80d4' 
  AND token = 'IW3gWxxC2u16A7Sj8rFf26pUIh8qCbFEJpl4PantUVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}