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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161af4c864b7119499f71a7f8eac38e0c3e7ed56e03f0857e3631a645814f3cb' 
  AND token = 'VqQQS7+h4REhaJbtFhgA09a7O+ydPu9Q1lCMpQT5gvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}