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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d567ab89b19dab889a314fb7f7f8ad932f2c7e58b272e2afbfbe0088bf1be92' 
  AND token = 'tWYMYIzel2X3Zxotl9nbb9LKQ+qJgqzXUd+9tj9W8FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}