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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d42a4f8002ba282bd5a2ded129d5036e9a171fe1a267df3a032381fbaf8344' 
  AND token = 'vueBq49fjxP2jdQrZsFcgt1rC/rRLooqxUlD/AW4VE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00149

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}