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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '867b2a1bad186c2b15aeafde8cd035a6cc989a7445ad5e8e04815863a6c7a8b6' 
  AND token = 'Jp+nUGImvVH4gLvHaIJXcm6hfGSYwNHWDM7Ga/gerHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}