SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6dcba510ad0f6dceccd61603e92f54388f10dcfa436c73ed1bfed5ed06085f' 
  AND token = 'HZP+KSbpAp88QD9vrVkvYpJRGZ5x4cyjAJNo49qk8UU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}