SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed9c77a567ce4d55f19a4cd3feace406534f07b9489941f95b3c84d17743e491' 
  AND token = 'sB4DsZvTZ5+7lB1YiJmTc/sj2CM1QyuEWQRKjt46VxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}