SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2c1b02e2a51e9baafc858b5865f997d3da1b0bdb21aa29eed89a4293608b3c' 
  AND token = 'B7P4KL4UuOohhpJavzJlEo2JxfYTiPpHP8bsmRDpaFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}