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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39d261e4ff719fd8f8f70051470871bbe86986ee420ae316c0ccb1e18748f734' 
  AND token = '6cDOp/ZqICaWkOeLIWCa0am0x4l27GiOK6Knds5Xd4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}