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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf0b1206bda5fba70200ade06ea41ecdd00f7503990de63eb2e6988ac3febb6' 
  AND token = 'vO2O4VUR0axE+XPFwXYMA90J6Ij2UhmRPNvL5Woqdqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}