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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f750fbd392a8f302d442b38c3aa4dc06938dad8c46de21e953d091acf7e5c962' 
  AND token = 'df0k9CMW/oHdI1nfWdIw3JlrjeWpMhYxW1977o3zOp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}