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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57de70f1f97bcb19fb0d5a64ea6c3fe20d3028306057b0742f8bfc26ff6bb14a' 
  AND token = 'lix67QxISKuKPu7QxgG/uH872Or5QuEbziU+SD2MAJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}