SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6da69520de9cbe0ec6c79aa88d435a2e7319edd12b184aabcdb225d9b3f63cd' 
  AND token = 'Ni/l7HZRH8V84MPFebLp+QH7BLSMrjYUMP/XTA/n4sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}