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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b87bf32e9ceff3ee81f50d082f2d53dacc4b7c2ecfda65bbc3b731265b9d727' 
  AND token = '/JyhNi0/ywetL3QhrnJozVO25ZhLaTR4FbcxBEoMnMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}