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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fe35036f900c7e920ac2353c1cd65e8b112bfb76b8e6b956860d1c2435c553b' 
  AND token = 'AZCmG55AgvZBajq2kotvbAliFcL179vfL2UrcttHgSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}