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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3779a9d11188a3b6d9e8a1bfdf98e603365783ceb61b9241bd37d477619a685f' 
  AND token = 'MIiMW0jGCOvQL5n8pl13P1hy4x91e+bPZsx77dDIObc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}