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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '766e1d469a07045eb880577f269f19f34c8dd2f1c2905f19678ee48092ba279c' 
  AND token = '/sQqGexrSu+NZqYSdZPO/NMGxSaEG8SDWy/KUWHCWNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}