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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c66078c775c572c4e38d1648aa0fbbe6bae9d5bc3101a97964a4c9f2164b1a' 
  AND token = 'ywphwkoLktiH4nC2ATeBwNJlmPvcTz0Zjc1Xg6XyzzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}